The Center for Immunity & Immunotherapies is seeking a Research Scientist interested in advancing our understanding of the pathogenesis of systemic autoimmunity and discovering novel therapeutic strategies to treat human disease.
The successful applicant will thrive in a fast-paced team environment in the laboratory of Dr. Shaun Jackson, as part of Dr. David Rawlings’ basic and translational immunology center. Potential projects for the selected candidate include studying how dysregulated B cell signaling promotes the pathogenesis of systemic autoimmunity, as well as developing targeted immunotherapies (using CAR T cells) to treat antibody-mediated disease.
Overall responsibilities include acquiring an in-depth understanding of the field in which they are working, and working with the PI, as well as independently, on the planning, design, execution, trouble-shooting, and interpretation of experiments. The successful candidate will carry out research/development activities including: establishment of murine bone marrow chimeras; immune subset analysis by multicolor flow cytometry; generating chimeric antigen receptor (CAR) T cells; managing rodent experimental cohorts; data presentation, experimental planning, and manuscript preparation. Good communication, organization, interpersonal, problem solving and creative thinking skills are required.
This position would be well-suited to an applicant desiring additional research experience prior to commencing MD and/or PhD graduate studies.
- Bachelor’s Degree in biology, microbiology, immunology, molecular biology or biochemistry.
- Prior experience in a laboratory setting.
- Masters/PhD in Immunology, or
- 2 years research experience in biochemistry, molecular biology, and tissue culture techniques is highly preferred.