Here at Seattle Children's we are united by a compelling mission: We provide hope, care and cures to help every child to live the healthiest and most fulfilling life possible. Seattle Children's Research Institute is among the top 5 in National Institutes of Health funding - a sign that our physician-scientists are leaders in research that improves the outlook for children with a wide range of conditions.
Come join our team!
The Nigam lab at the Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute and the University of Washington invites applications for a postdoctoral position. The PI is Dr. Vishal Nigam, a physician scientist who cares for children born with cardiac defects. Dr. Nigam is specifically looking to mentor an independent self-starter who can work in autonomous settings but also collaborate when needed. You would be using in vitro, human iPS cardiomyocyte, small animal, and large animal models to understand the role of biomechanical stimuli in normal and pathologic cardiac development. The goal of this research is help improve the understanding of the pathogenesis of cardiac defects.
The successful candidate will perform both exacting bench work and statistical and bioinformatics analyses on the resulting RNA-Seq/CHiP-Seq/single cell-Seq datasets using MatLab and R. The candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation involving primary embryonic cardiomyocyte cell culture, genetic mouse models, and human iPS cells. The candidate will be mentored to independently move projects forward, write papers, and apply for F32 or equivalent grants.
The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses. Prior experience with human iPS cell culture and R programming would be beneficial. Creative, big-picture thinking and dedication to cardiovascular research are essential.
The selected candidate will join the vibrant research community at CDBRM, located in a newly renovated building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment. Initial appointment will be for one year, with extension contingent on funding and performance.
Required Education/Experience: - PhD in specialty area from an accredited university training program - Experience using basic research techniques of specialty area Required Credentials: N/A Preferred: - Previous experience in RNA-Seq and ChIP-Seq data analysis - Previous experience working with mouse models - Experience in protocol and manuscript development and in grant writing.
- PhD in specialty area from an accredited university training program
- Experience using basic research techniques of specialty area
- Previous experience conducting research in the pediatric arena
- Experience in protocol and manuscript development and in grant writing