The Nigam lab at the Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute and the University of Washington invites applications for a postdoctoral position. Work in the Nigam lab uses basic science and translational approaches to improve the care of children born with severe cardiac defects. One of the lab’s two main research programs in the lab is focused on understanding how perturbations in biomechanical stimuli result in cardiac lesions, such as Hypoplastic Left Heart Syndrome. The other focus seeks to elucidate and find novel treatments for the systemic inflammation that occurs after exposure to cardiopulmonary bypass, which is required for the majority of cardiac surgeries.
The successful candidate will perform both exacting bench work and analyses on the resulting RNA-Seq/CHiP-Seq/single cell-Seq/CyTOF datasets. The candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants.
The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses. Prior experience with human iPS cell culture and R programming would be beneficial. Creative, big-picture thinking and dedication to cardiovascular research are essential.
The selected candidate will join the vibrant research community at CDBRM, located in a newly renovated building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment. Initial appointment will be for one year, with extension contingent on funding and performance.
- PhD in specialty area from an accredited university training program
- Experience using basic research techniques of specialty area
- Previous experience conducting research in the pediatric arena
- Experience in protocol and manuscript development and in grant writing