Fellow - PhD

Job ID 2020-35647
Area of Interest
Research & Development
Location Name
Jack R MacDonald Building
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Dev Biology & Regenerative Med
Day Shift
Primary Location : City
Primary Location : State/Province

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE


As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.


Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 


Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.


The Nigam lab at the Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute and the University of Washington invites applications for a postdoctoral position.  Work in the Nigam lab uses basic science and translational approaches to improve the care of children born with severe cardiac defects. One of the lab’s two main research programs in the lab is focused on understanding how perturbations in biomechanical stimuli result in cardiac lesions, such as Hypoplastic Left Heart Syndrome. The other focus seeks to elucidate and find novel treatments for the systemic inflammation that occurs after exposure to cardiopulmonary bypass, which is required for the majority of cardiac surgeries.


The successful candidate will perform both exacting bench work and analyses on the resulting RNA-Seq/CHiP-Seq/single cell-Seq/CyTOF datasets. The candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants.


The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses.  Prior experience with human iPS cell culture and R programming would be beneficial. Creative, big-picture thinking and dedication to cardiovascular research are essential.


The selected candidate will join the vibrant research community at CDBRM, located in a newly renovated building in downtown Seattle.  A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment.  Initial appointment will be for one year, with extension contingent on funding and performance.


Required Education/Experience:
- PhD in specialty area from an accredited university training program
- Experience using basic research techniques of specialty area

- Previous experience conducting research in the pediatric arena
- Experience in protocol and manuscript development and in grant writing

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.


The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.


Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.


Sorry the Share function is not working properly at this moment. Please refresh the page and try again later.
Share on your newsfeed