Research Scientist I

Job ID 2020-36213
Area of Interest
Research & Development
Location Name
Jack R MacDonald Building
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Immunity & Immunotherapies
Day Shift
Primary Location : City
Primary Location : State/Province

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE


As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.


Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 


Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.


We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.


The Acharya lab ( at Seattle Children’s Research Institute is hiring a scientist to join a rapidly expanding research program on signaling pathways that regulate immune response to viruses. Research in our group is focused on studying mechanisms that lead to efficient antibody response to viruses and how these get dysregulated during development of autoimmunity. We also collaborate with the James lab and Rawlings lab at Seattle Children’s to used gene editing technology in B cells to manipulate genes and study changes in antibody responses For this position, we are seeking a highly motivated scientist to work with the group in performing experiments related to flow cytometry, ELISA, western blots and tissue culture experiments, and experiments involving immunization of mice and harvesting target tissues from mice. Additionally, the applicant will be responsible for data anlalysis, presentation of results and working together with other scientists in the group.



  1. Design experiments to perform flow cytometry, western blot.
  2. Design experiments to study activation of signaling proteins in B cells
  3. Perform ELISA on serum samples acquired from mice to study antibody response
  4. Assist with genotyping and management of mouse colony
  5. Immunize mice with different viral antigens
  6. Perform experiments on tissues harvested from mice.
  7. Analyse data and present data at group meetings.
  8. Contribute to writing for publication of results; generate figures for papers and grants.




Required Education/Experience:
- Bachelor’s Degree in an engineering or scientific discipline
- Prior experience in a laboratory setting; may include relevant educational programs.

Required Credentials:
- N/A

- Working knowledge of area of research specialization
- Experience with research laboratory techniques.

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.


The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.


Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.


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