Postdoctoral Fellow - Kappe Lab

Job ID 2020-36422
Area of Interest
Research & Development
Location Name
307 Westlake
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Regular
Department
Global Infectious Disease
Shift
Day Shift
Primary Location : City
Seattle
Primary Location : State/Province
WA

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

 

As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.

 

Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 

 

Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

 

We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.

Overview

The malaria research laboratory of Dr. Stefan Kappe (https://www.seattlechildrens.org/research/centers-programs/global-infectious-disease-research/research-areas-and-labs/kappe-lab/) at the Center for Global Infectious Disease Research (CGIDR), Seattle Children’s Research Institute (SCRI), is recruiting a Postdoctoral Scientist to study the immune mechanisms that mediate protection against malaria parasites. The Kappe laboratory has pioneered the use of genetically attenuated parasites that arrest and die in the liver as anti-malaria vaccines. We have shown in humans and mice that the arrest and death of these genetically attenuated parasites in the liver induces a complex immune response that protects the host from future malaria parasite infections.  Projects in the Kappe laboratory aim to identify which parasite antigens are presented to adaptive immune cells, what factors influence the durability of the adaptive immune response and how innate immunity regulates the magnitude and quality of protective anti-malaria adaptive immunity.

 

This position offers an extraordinary opportunity to work in a vibrant, collaborative, multi-disciplinary environment. The successful candidate will have a keen interest in working with Plasmodium as a parasite of global health importance to identify how basic parasite biology shapes the immune response to infection and the translation of novel immunological observations into the improvement of anti-malaria vaccines.

 

Along with a curriculum vitae, candidates must provide a cover letter detailing the following:

  • Current and previous research experience
  • Expected starting date
  • Your interest in working with the malaria parasite
  • What you hope to achieve during your tenure in the position
  • Your career ambitions and research goals

Requirements

Required Education/Experience:

  • Ph.D. in immunology, microbiology or a related scientific discipline
  • Experience in immunological analyses in humans and animal models of infection and vaccination
  • Willingness to work with a diverse team of scientists, including postdocs, students and technicians.
  • The ability to work independently as well as collaboratively

Beneficial qualifications (not required)

  • Experience working with infectious disease models, especially apicomplexan parasites

Along with a curriculum vitae, candidates must provide a cover letter detailing the following:

  • Current and previous research experience
  • Expected starting date
  • Your interest in working with the malaria parasite
  • What you hope to achieve during your tenure in the position
  • Your career ambitions and research goals

Preferred:
- Previous experience conducting research in the pediatric arena
- Experience in protocol and manuscript development and in grant writing

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

 

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.

 

Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.

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