Clinical Postdoctoral Fellow - PhD

Job ID 2021-38028
Area of Interest
Research & Development
Location Name
307 Westlake
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Regular
Department
Global Infectious Disease
Shift
Day Shift
Primary Location : City
Seattle
Primary Location : State/Province
WA

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

 

As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.

 

Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 

 

Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

 

We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.

Overview

We seek an enthusiastic and collaborative postdoctoral fellow to join our Translational Immunology Group.  The successful candidate will play a key role in characterizing functionality of immune cells in the context of tuberculosis, nontuberculous mycobacteria and positive strand RNA viruses e.g., SARS-CoV-2.  Previous experience in human immunology and cellular immunoassays, including multiparametric flow cytometry, is required.  Excellent organizational and communication skills are essential.

Primary Responsibilities:

  • Assessment of immunological endpoints in vaccine clinical trials including assay development and validation.
  • Contribute to writing clinical study reports, statistical analysis plans and grant applications.
  • Perform specimen processing and shipping for domestic and international sites.
  • Work closely under supervision to implement research projects that further the understanding and development of effective vaccines.
  • Committed participation as a team member to support experimental design, immunoassay development and methodology following scientific literature review, quality standards and discussion with peers, as required.
  • Responsible for following Standard Operating Procedures and development/optimization/ qualification/validation reports for immunoassays.
  • Responsible for performing assay development, optimizations, and validations as a primary lead and/or in collaboration with others.
  • Participate in laboratory audits to ensure GCLP-like compliance and assist with clinical training activities.
  • Records procedures, outcomes and observations in lab notebook following established guidelines.
  • Utilize established mathematical and scientific techniques to compile and critically analyze and interpret data.
  • Communicate with research management on a regular basis.
  • Prepare manuscripts for publication in peer reviewed journals.
  • Presents research at group and internal/external scientific meetings.
  • Contributes to maintenance of the sample repository including sample tracking procedures.

Requirements

Required Education/Experience:
-Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program
- Experience using basic research techniques of specialty area

Preferred:

  • Experience in microbiology and/or infectious diseases.
  • Experience and skills with PBMC processing, humoral, and/or cellular immunology and human T- and B-cell based functional assays (e.g., >10-color flow cytometry panels, ELISPOT, ELISA and antibody neutralization).
  • Deep understanding of immunology and/or human biomarker research.
  • A strong publication track record.
  • Experience working under Biosafety Level 2 or 3 (BSL-2/BSL-3) conditions.
  • Excellent oral and written communication skills in English.
  • Proficiency in MS Office, scientific data/graphics programs, and biostatistics.
  • Must be self-motivated, highly organized and be able to work in a team environment.

 

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

 

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.

 

Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.

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