Research Scientist II

Job ID 2021-39030
Area of Interest
Research & Development
Location Name
Jack R MacDonald Building
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Immunity & Immunotherapies
Day Shift
Primary Location : City
Primary Location : State/Province

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE


As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.


Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 


Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.


We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.


Seattle Children’s research institute is seeking a talented and motivated Research Scientist II to join cellular therapy group in Dr. David Rawlings lab at center for immunity and immunotherapies. Rawlings lab utilizes various gene editing technologies to generated engineered regulatory T cells (EngTregs) for its potential application to treat autoimmunity. A successful candidate is expected to contribute towards the ex-vivo generation of EngTregs and testing its efficacy in various in vivo mouse models to support our cellular therapy projects. The candidate will have opportunities for growth and encourage to learn new skills grow in a though provoking environment.


Key Responsibilities:

  • Plan, execute, analyze, and present data from in vivo and invitro studies that support the cellular therapy projects.
  • Present research findings to lab group and collaborators.
  • Analyze samples using multiparameter flowcytometry.
  • Analysis of experimental data using Flow jo, PRISM, MS office etc.
  • Ability to manage multiple projects simultaneously and work with different team members.


Required Education/Experience:
- Bachelor's Degree in biology, microbiology, immunology, molecular biology or related discipline; Minimum of two (2) years experience in a related area/laboratory setting. 




- BS or MS in biology, microbiology, immunology, molecular biology, or related discipline

- 2+ years of experience in conducting in vivo studies using mouse models.

- Experience with sterile tissue culture, and with basic molecular and cellular biology techniques required

- Skillful in handling rodent.

- Expertise with various in vivo skills (iv, ip and RO injections) blood/tissue collection.

- Detail oriented

- Strong communication skills and ability to work effectively in a multidisciplinary team environment.

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.


The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.


Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.


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