Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE
As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.
Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine.
Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.
We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.
A fully supported postdoctoral position is available in the Coler Translational Research Group to characterize immune response of novel vaccines for infectious diseases including schistosomiasis.
Previous experience in human immunology - functional antibody-based and cellular immunoassays, including multiparametric flow cytometry - is required.
The postdoctoral fellow will develop expertise in the assessment of vaccine mediated immune responses and systems immunology. A key aspect will include combining information from multiple levels such as genes, proteins and whole cells to gain a clear, multi-scale understanding of vaccine function during infection and disease. The fellowship is designed to prepare the post-doctoral level trainee for a career in a non-profit biotechnology- and multidisciplinary setting.
Excellent organizational and communication skills are required.
• A PhD with related laboratory experience in Parasitology, Immunology, Pathobiology, Microbiology or similar field
• A strong track record of publication
• Experience and skills in immunology and/or cellular biology assays
• Experience working with small animal models of infectious diseases
• Experience working under Biosafety Level 2 or 3 (BL2/BL3) conditions
• Willingness and ability to work under BL3 conditions with appropriate training
• Excellent oral and written communication skills in English
• Must be self-motivated, organized and be able to work within a team
• Cellular immunology and T- and B-cell based assays (e.g., >10-color flow cytometry panels, B cell ELISpot (ASC), T cell cytokine ELISpot, ADCC, cytokine multiplex assays)
• Proficiency in MS Office, scientific data/graphics programs, flow cytometry software, and biostatistics
• Design and execute hypothesis-driven research projects that advance the development of vaccine delivery platforms and generate effective vaccines for infectious diseases
• Assessment of immunological endpoints in vaccine clinical trials including assay development and validation
• Prepare manuscripts for publication in high-profile peer reviewed journals
• Presents research at internal/external scientific meetings
• Participate in grant writing
• Communicate with research management on a regular basis
• Records procedures, outcomes and observations in a lab notebook format following established guidelines
• Utilizes established mathematical and scientific techniques, including statistical analyses, to compile and critically analyze and interpret data
• Contributes to or leads maintenance of the sample repository including sample tracking procedures
• Supervision of research assistant(s) and/or associate(s)
Knowledge, Skills and Abilities:
• Work independently and in a team under general supervision
• Able to manage time effectively
• Able to use experience and judgment to plan and accomplish goals
• Able to write and perform multiple scientific protocols and procedures independently
• Good written and oral communication skills; ability to communicate tactfully, professionally, and effectively
• Experience writing manuscripts and grants helpful
• Ability to work accurately with close attention to detail
Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.
The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.
Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.