Process Development Engineer II

Job ID 2021-39860
Area of Interest
Research & Development
Location Name
Olive Lab at MPW
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Regular
Department
SC Therapeutics (SCTx)
Shift
Day Shift
Primary Location : City
Seattle
Primary Location : State/Province
WA

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

 

As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.

 

Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 

 

Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

 

We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.

Overview

Accountable for designing and performing process development activities in the GMP biologics manufacturing facility covering a variety of process steps and process goals aimed at creating new manufacturing processes or improving existing processes. Collaborates with PD management on process development strategy, contributing current knowledge and implementing technical expertise required to make meaningful advances in manufacturing and operations of the GMP biologics manufacturing facility in concert with strategic goals and objectives.

 

Responsibilities
• Work in teams to develop upstream and downstream processes for biologics manufacturing
• Technology development to reduce the cost and improve the efficiency of manufacturing
• Transfer processes to manufacturing facility

 

Requirements

Required Qualifications

• MS in Biomedical Engineering, Biotechnology, or related field. Or 2+ years experience in process development
• Experience in either upstream or downstream, preferably in a process development capacity

 

Preferred Qualifications
• Experience in upstream technology, including bioreactor cell culture, transfection, scale-up, robotics, and automation
• Experience in downstream processing technology, including centrifugation, clarification, tangential flow filtration, chromatography, and fill/finish
• Experience in analytical assays - qPCR, ddPCR, flow cytometry, ELISA, and lentiviral transduction
• Experience with design of experiments (DOE) and multivariate data analysis (MVDA) using statistical software packages
• Programming and data analysis with Python and/or R
• Experience with process tech transfer to manufacturing facilities

 

In accordance with new Washington law for healthcare workers, Seattle Children’s requires that all staff be fully vaccinated against COVID-19 on or before October 18, 2021, or before beginning employment for start dates after October 18th.

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

 

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.

 

Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.

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