Seattle Children's Hospital

Postdoctoral Fellow, Research - Coler Lab

Job ID 2022-45454
Area of Interest
Research & Development
Location Name
307 Westlake
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Global Infectious Disease
Day Shift
Primary Location : City
Primary Location : State/Province
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A fully supported Postdoctoral Scholar position is available in the *Seattle Tuberculosis Research Advancement Centers (SEA-TRACs) and the Coler Translational Research Group to characterize immune response of novel vaccines and immune pathology associated with tuberculosis and co-morbidities. Previous experience in cellular immunology, including multiparametric flow cytometry, is required.


The postdoctoral fellow will receive focused mentoring and training in laboratory and clinical settings and will develop expertise in the assessment of vaccine mediated immune responses and systems immunology. A key aspect will include combining information from multiple levels such as genes, proteins and whole cells to gain a clear, multi-scale understanding of vaccine function during infection and disease.


The fellowship is designed to prepare the post-doctoral level trainee for a career in a non-profit biotechnology- and multidisciplinary setting. Excellent organizational and communication skills are required.


Individuals from racial and ethnic groups that have been shown by the National Science Foundation to be underrepresented in health-related sciences on a national basis are encouraged to apply. The following racial and ethnic groups have been shown to be underrepresented in biomedical research: Blacks or African Americans, Hispanics or Latinos, American Indians or Alaska Natives, Native Hawaiians, and other Pacific Islanders.


Primary Responsibilities:
• Assessment of cellular, molecular and computational immunological endpoints in preclinical projects
• Contribute to study reports, statistical analysis plans and grant applications
• Work closely under supervision to implement research projects that further the understanding and development of effective vaccines
• Committed participation as a team member to support experimental design, developing immunoassay
methodology following scientific literature review, quality standards and discussion with peers, as required
• Responsible for following Standard Operating Procedures
• Records procedures, outcomes and observations in lab notebook following established guidelines
• Utilize established mathematical and scientific techniques to compile, critically analyze and interpret data
• Communicate with research management on a regular basis
• Prepare manuscripts for publication in peer reviewed journals
• Presents research at group and internal/external scientific meetings
• Contributes to maintenance of the sample repository including sample tracking procedures

Knowledge, Skills and Abilities:
• Work as a member of a collaborative team under general supervision
• Able to use experience and judgment to plan and accomplish goals
• Able to perform multiple scientific protocols and procedures
• Good written and oral communication skills; ability to communicate tactfully and effectively
• Experience writing manuscripts and grants helpful
• Ability to work accurately with close attention to detail
• Familiarity with current immunological or microbiological assays such as: Flow cytometry, ELISpots, Luminex,
antibody neutralization, and ELISA
• Proficiency with appropriate usage of statistical methods for data analysis
• Extensive working knowledge with data analysis and graphing software such as FLowJo, Prism, and/or Jump
• Ability to maintain confidentiality of sensitive information
• Ability to work with co-workers and outside agencies professionally and tactfully
• Possess a work ethic that includes team orientation, neatness, dependability, punctuality, and accuracy

*Read more on this PDF (


Required Education/Experience:
-Doctorate degree (PhD/DVM/MD) in Immunology, Microbiology, Cellular & Molecular Biology or similar field.
- Experience using basic research techniques of specialty area

Required Credentials:


- Experience and skills in cellular immunology and T- and B-cell based assays (e.g., >10-color flow cytometry panels, B cell ELISpot (ASC), T cell cytokine ELISpot, ADCC, cytokine multiplex assays)
- Deep understanding of immunology and/or human biomarker research
- Proficiency in MS Office, scientific data/graphics programs, flow cytometry software, and biostatistics
- A strong track record of publication
- Experience working under Biosafety Level 2 or 3 (BL2/BL3) conditions
- Willingness and ability to work under BL3 conditions with appropriate training
- Experience working with small animal models of infectious diseases
- Excellent oral and written communication skills in English
- Must be self-motivated, highly organized and be able to work on teams


In accordance with new Washington law for healthcare workers, Seattle Children’s requires that all staff be fully vaccinated against COVID-19 on or before October 18, 2021, or before beginning employment for start dates after October 18th.

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE


As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.


Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 


Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.


We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.

Covid-19 Vaccination

In accordance with Washington state law, Seattle Children’s requires that all employees be fully vaccinated against COVID-19. All offers are contingent and your vaccine status will be verified at onboarding.

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.


The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.


Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.


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