Postdoctoral Fellow

Job ID 2022-46183
Area of Interest
Research & Development
Location Name
Other Off-Site Location
FTE/Hours per pay period
1.0 FTE (80 hours per bi-weekly pay periods)
Work Status
Regular
Department
Dev Biology & Regenerative Med
Shift
Day Shift
Primary Location : City
Seattle
Primary Location : State/Province
WA
Hot Job
Yes

Responsibilities

The Paquette lab at the Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute and the University of Washington invites applications for a postdoctoral position. The Paquette lab uses placental ‘omics data to investigate the developmental origins of health and disease hypothesis. More information can be found here: http://depts.washington.edu/cdbrm/wordpress/research-labs-center-for-developmental-biology-and-regenerative-medicine/paquette-lab/.

 

The candidate will be involved in the analysis of placental microRNA and mRNA data, with a focus on integration of this data to study the relationship between prenatal phthalate exposure and spontaneous preterm birth. There will be opportunities to build upon these research questions to investigate other exposures and infant health outcomes; as well as to generate and integrate more omics data in key pregnancy tissues. This candidate will work closely with the ECHO PATHWAYS consortium, which is a multi-PI multi site consortium based out of the University of Washington. ECHO PATHWAYS brings together three cohorts to focus on multiple prenatal chemical exposures, whole genome placental transcription, and child neurodevelopmental and respiratory outcomes. The post-doctoral fellow will be expected to follow ECHO PATHWAYS guidelines for data analysis and publication.

 

This lab is an ideal place for a postdoctoral candidate because of the highly interdisciplinary nature of our work, collaborations across the UW community and beyond, and opportunity to develop unique projects within this space. Our lab is well funded by multiple grants, providing ample resources to pursue cutting edge science and advance your career. The PI is committed to career development of trainees, and you will receive strong mentorship and be provided with opportunities to present your research locally as well as at national meetings. Other postdoctoral fellows in this group have recently received international recognition for their work at research conferences.

 

There are ample opportunities to develop a strong computational background within SCRI; as the Research Informatics team provides regular classes on key concepts in this field and holds routine office hours. Seattle is a hub for bioinformatics and computational biology research, and are ample opportunities to attend seminars and interface across the University of Washington; as well as from organizations such as the Brotman Baty Institute and the Pacific Northwest Metabolomics core. The selected candidate will join the vibrant research community at CDBRM, located in a newly renovated building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment. Initial appointment will be for one year, with extension contingent on funding and performance.

 

Successful candidates should be highly motivated with an outstanding publication record (at least one first-author research paper published in peer-reviewed international journal) and strong work ethic. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants. Dedication and experience with molecular epidemiology, biostatistics, environmental exposures, computational biology, microRNA sequencing and/or placental biology are high priority areas. The candidate is expected to have formal training in biostatistics and/or epidemiology, and experience with working with the R programming language.

Requirements

Required Education/Experience:
-Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program
- Experience using basic research techniques of specialty area

Required Credentials:
N/A

Preferred:

  • Formal training biostatistics and/or epidemiology
  • Research background in environmental exposure analysis, perinatal, placental, or reproductive biology,
  • Experience with working with the R programming language and on high throughput bioinformatics data
  • Expertise conducting formal mediation analyses
  • Systems Biology/Integrative pathway expertise
  • Experience working with microRNA sequencing data in large cohort studies

To apply for this position; please provide a (1) curriculum vitae and (2) a cover letter detailing your research goals, interest in working within the perinatal biology space, and any other information that is not covered in the CV that may be relevant.

 

In accordance with new Washington law for healthcare workers, Seattle Children’s requires that all staff be fully vaccinated against COVID-19 on or before October 18, 2021, or before beginning employment for start dates after October 18th.

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible.  Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

 

As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.

 

Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 

 

Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

 

We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.

Covid-19 Vaccination

Seattle Children’s requires that all employees be fully vaccinated against COVID-19. All offers are contingent and your vaccine status will be verified at onboarding.

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

 

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.

 

Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.

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