The Rajagopal lab (https://www.seattlechildrens.org/research/centers-programs/global-infectious-disease-research/research-areas-and-labs/rajagopal-lab/) has an opening for a postdoctoral position to study molecular mechanisms during microbial pathogenesis. Area of interest include the pathogenesis of Group B Streptococcus and studies on its toxin. The position will involve isolation and purificationof lipid toxins and elucidating the role of the toxin and toxoid derivatives in animal models of pregnancy associated infections and neonatal disease.
Responsible for independently evaluating, selecting, and applying standardized scientific procedures and techniques to carry out research/development activities in a particular scientific discipline. Has broad knowledge of principles, practices and procedures of field of specialization. Relies on experience and judgment to plan and accomplish goals. Makes detailed observations, analyzes and interprets data and writes manuscripts/grant proposals. Collaborates with principal investigator, taking direct responsibility for carrying out research and development activities. Considerable effort (25% or more) may be dedicated to seeking independent outside research funding.
Provide direct care and assume primary responsibility for clinical management of patients in ambulatory, operating room, emergency department, and inpatient settings. Obtain patient histories, perform physical examinations, order, perform, and interpret diagnostic tests, prescribe medications, and develop treatment plans. Direct or participate in case management and continuing care. Collaborate, refer, and consult with department attending physicians, specialists, and other members of the health care team to deliver effective, efficient, safe, and high quality care. Contribute to organizational and departmental continuous performance and quality improvement projects. Participate in education and research efforts for patients, families, and the health care team.
Seattle Children's is looking for a Registered Nurse - Cardiac ICU, 0.9 FTE, Nights, to join our team!
As an integral member of the Health Care Team, the RN functions within the Scope of Practice as defined by the State, the ANA Scope and Standards for Pediatric Nursing Practice, and adheres to Seattle Children’s policies/procedures and guidelines of care.
Responsible for providing safe, family centered patient care. Using the Nursing Care Process, the RN is responsible for assessing, planning, implementing and evaluating patient care in a collaborative method with the patient and patient’s family, significant others, and members of the health care team.
May be required to provide supervision and delegation of tasks to Nurse Technicians, Licensed Practical Nurses, Certified Medical Assistants, and others as defined by the State Administrative Code.
Assists in meeting Seattle Children’s strategic goals by incorporating the initiatives to support the strategic plans into the daily work, i.e. Continuous Performance Improvement (CPI), ART, etc.
In accordance with House Bill 1155 (effective January 1, 2020), the following areas have clinical unpredictable needs and as a result will have a call obligation within their nursing positions: Apheresis, Cardiac Cath Lab, Dialysis, ECMO, Home Care Services, Imaging Services (including GI Procedures), Perioperative Services, and Transplant Coordinators.
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Provides mental health services to children, adolescents, and families as part of the Cancer Care Psychosocial Services team. Assist in promotion of culturally appropriate family-centered care and wellness of patients and families by identifying, interpreting, and reducing psychosocial factors contributing to illness. Counsel and aid patients and their families to understand and accept medical recommendations and options. Provide mental health services and crisis intervention to children, adolescents, and families in a manner which results in improvements in the child and family’s functioning in multiple life domains and is cost effective. Assess and assist with non-medical problems interfering with effective patient care. Interview, coordinate, and plan programs and activities to meet the social and emotional needs of patients and/or patients’ family.
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Seattle Children's Therapeutics (SCTx) at Seattle Children's Research Institute (SCRI) is an exciting new venture aimed at leveraging a biotech industry business model in a non-profit context to bring cutting edge, curative technologies and therapies to defeat pediatric cancer and beyond. Our immunotherapies offer hope to families who have exhausted other treatment options - our work directly saves lives. We are seeking a bright, enthusiastic, and highly-motivated biologist to join our Research and Development group. This position contributes to a team focused on translating tumor immunotherapy from the bench into pediatric patients with cancer. We look for people who are inspired by our mission and who would fit in well with the collaborative, rigorous, and entrepreneurial spirit of our research team culture.
The primary purpose of this position is to develop and analyze the potential of lentiviral vectors carrying differentially regulated payloads, including chimeric antigen receptors (CARs), to create more efficacious cell therapies for solid tumors. Under the direction of a senior research scientist, the successful candidate will use their established molecular and cellular biology skill sets to create both tumor cell lines and primary T cells and develop and implement assays to assess the cytotoxic and therapeutic potential of the T cell products, both in vitro and in vivo. Lab techniques include basic and advanced molecular biology and operation of Incucyte, MSD, flow cytometers, cell sorters, and liquid handling robots.
The ideal candidate will have significant work experience in flow cytometry, tissue culture, molecular biology, and immunology. This position will be extensively involved in designing experiments, implementing new strategies, generating data, analyzing results, and preparing reports in support of funded research studies. To ensure successful project completion and teamwork, the incumbent will demonstrate strong critical thinking abilities, ability to prioritize and perform multiple tasks in a dynamic environment, meet deadlines, and excellent written, verbal, and interpersonal communication skills. In addition, the successful candidate will participate and present data in weekly lab meetings, maintain an up-to-date and well-organized electronic lab notebook, and rigorously follow Good Laboratory Practice (GLP) guidelines. Above all, a willingness to learn, passion for our mission, collaboration, and creativity are crucial for success at Seattle Children's Therapeutics (SCTx).
Seattle Children’s Employer Highlights:
• Leader in Pediatric Care: Because of our people, Seattle Children’s is recognized as a leading teaching, research and specialty care center at the forefront of pediatric care.
• Competitive Benefits: We support a healthy work–life balance. Our benefits include employee care, paid time off, health insurance and retirement savings.
• Transportation Discounts: Company bike program, on-site zip cars, unlimited ORCA transit pass, daily commute bonus provided to staff who us alternate methods of travel to/from work, company vanpools.
• Diversity/Inclusion: We strive to maintain an atmosphere that reflects our values of inclusion by providing effective and respectful care compatible with each patient and family's beliefs, values, and heritage.
Oversee and supervise the day-to-day operations of the housekeeping services including, but not limited to, staff scheduling, job assignments, performance management, and training. Function as primary contact for all ES needs throughout the organization. Ensure services are provided in a timely, consistent and collaborative manner while ensuring standards and procedures are followed.
Night Shift
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Seattle Children’s research institute is seeking a talented and motivated Research Scientist II to join cellular therapy group in Dr. David Rawlings lab at center for immunity and immunotherapies. Rawlings lab utilizes various gene editing technologies to generated engineered regulatory T cells (EngTregs) for its potential application to treat autoimmunity. A successful candidate is expected to contribute towards the ex-vivo generation of EngTregs and testing its efficacy in various in vivo mouse models to support our cellular therapy projects. The candidate will have opportunities for growth and encourage to learn new skills grow in a though provoking environment.
Key Responsibilities:
- Plan, execute, analyze, and present data from in vivo and invitro studies that support the cellular therapy projects.
- Present research findings to lab group and collaborators.
- Analyze samples using multiparameter flowcytometry.
- Analysis of experimental data using Flow jo, PRISM, MS office etc.
- Ability to manage multiple projects simultaneously and work with different team members.
Provide direct care and assume primary responsibility for clinical management of patients in ambulatory or inpatient settings. Obtain patient histories, perform physical examinations, order, perform, and interpret diagnostic tests, prescribe medications, and develop treatment plans. Direct or participate in case management and continuing care. Collaborate, refer, and consult with department attending physicians, specialists, and other members of the health care team to deliver effective, efficient, safe, and high quality care. Contribute to organizational and departmental continuous performance and quality improvement projects. Participate in education and research efforts for patients, families, and the health care team.
Efficiently, accurately, and respectfully process incoming requests (primarily via phone) and initiate crisis code procedures for all hospital emergencies. Maintain and interpret call schedules and track telecom equipment using multiple software applications with superlative customer service skills. Concisely describe appropriate and effective information to callers based on caller inquiries.
TB remains a serious global health problem and there is an urgent need for new therapeutic agents. Work within our group focusses on the development of new anti-tubercular agents. The Parish Lab (https://www.linkedin.com/in/tanya-parish-a564056/) is seeking a qualified chemist at the post-doctoral level to conduct synthetic/medicinal chemistry in the area of tuberculosis.
The candidate will work on a research project to develop novel inhibitors of protein secretion in the global human pathogen Mycobacterium tuberculosis. The candidate will be responsible for the design, synthesis and characterization of small molecules for drug discovery, as well as analytical chemistry.
Description of Responsibilities:
• Conduct a research and development project
• Design and implement research plans
• Troubleshoot and solve experimental and technical problems
• To prepare and present papers, reports, and presentations of current research work
• Write manuscripts and assist with grant preparation
• Oversee quality control and data integrity
Specific duties include:
• Design, synthesis, purification and characterization of small molecules as candidate anti-tubercular agents
• Use of analytical chemistry techniques/methods.
• Support of in vitro ADME studies.
Provide direct care and assume primary responsibility for clinical management of patients in ambulatory, operating room, emergency department, and inpatient settings. Obtain patient histories, perform physical examinations, order, perform, and interpret diagnostic tests, prescribe medications, and develop treatment plans. Direct or participate in case management and continuing care. Collaborate, refer, and consult with department attending physicians, specialists, and other members of the health care team to deliver effective, efficient, safe, and high quality care. Contribute to organizational and departmental continuous performance and quality improvement projects. Participate in education and research efforts for patients, families, and the health care team.
Seattle Children's Hospital (SCH) Outpatient Psychiatry department is seeking a clinical child and adolescent psychologist based at the main campus in Seattle, Washington. This position will join a team of psychologists and master's level therapists providing diagnostic evaluations, individual therapy, group therapy, and will join the Dialectical Behavioral Therapy (DBT) - Intensive Outpatient Program. Preferred candidates will have training and experience providing DBT therapy to adolescents, and interest in cognitive-behavioral therapy treatment of youth with depressive and mood disorders, and psychosis. The position will primarily be providing direct services in the clinic setting, with some limited opportunity for telehealth services provided from the employee’s home.
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Seattle Children's is looking for an experienced Social Worker to be a Supervisor within our awesome Social Work team! This is a working supervisor position with 40% of the role dedicated to overseeing a team of 8-10 Social Workers and 60% of the role in a direct Social Work position. The 60% portion of the work will focus on acute and chronic medically complex patients.
Our Social Work department is a positive and supportive group of dedicated people who have a passion for helping others navigate their healthcare experience. If you are a compassionate patient advocate and love working in a collaborative team environment, come join us!
Social Work Supervisor duties include:
- Oversee the delivery of clinical social work services and provide supervision to social work staff within a specific program area.
- Serve in a significant leadership role for the department and hospital.
- As a senior clinician, provide advanced clinical social work services to children with acute and chronic illness, their families, the staff of Seattle Children’s Hospital and the community in a managed care environment.
- Lead in the promotion of culturally appropriate family-centered care and wellness of patients and families by identifying, interpreting, and reducing psychosocial factors contributing to illness.
- Rely on extensive experience and judgment to plan and accomplish goals for staff.
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As an integral member of the Health Care Team, the RN functions within the Scope of Practice as defined by the State, the ANA Scope and Standards for Pediatric Nursing Practice, and adheres to Seattle Children’s policies/procedures and guidelines of care. Responsible for providing safe, family centered patient care. Using the Nursing Care Process, the RN is responsible for assessing, planning, implementing and evaluating patient care in a collaborative method with the patient and patient’s family, significant others, and members of the health care team. May be required to provide supervision and delegation of tasks to Nurse Technicians, Licensed Practical Nurses, Certified Medical Assistants, and others as defined by the State Administrative Code. Assists in meeting Seattle Children’s strategic goals by incorporating the initiatives to support the strategic plans into the daily work, i.e. Continuous Performance Improvement (CPI), ART, etc.
In accordance with House Bill 1155 (effective January 1, 2020), the following areas have clinical unpredictable needs and as a result will have a call obligation within their nursing positions: Apheresis, Cardiac Cath Lab, Dialysis, ECMO, Home Care Services, Imaging Services (including GI Procedures), Perioperative Services, and Transplant Coordinators.
Perform laboratory procedures and investigative work as part of ongoing research projects. Perform a variety of moderately complex investigative/technical procedures; interpret results and determine whether they are consistent with experimental goals; modify experimental procedures or technique to obtain optimal experimental results; assist in the assembly, organization and interpretation of data. Assist in the planning, execution and analysis of research experiments.
Seattle Children's Therapeutics (SCTx) at Seattle Children's Research Institute (SCRI) is an exciting new venture aimed at leveraging a biotech industry business model in a non-profit context to bring cutting edge, curative technologies and therapies to defeat pediatric cancer and beyond. Our immunotherapies offer hope to families who have exhausted other treatment options - our work saves lives. This position will support the GMP Biologics Manufacturing team as we aim to develop our internal manufacturing capabilities for key starting materials to accelerate our cell therapy manufacturing program, including viral vectors, plasmids, and protein therapeutics.
The focus of the GMP Biologics Manufacturing team is to build an internal CDMO function to eliminate our biggest hurdle to delivering cures to kids. The sourcing of viral vectors is an expensive and time-consuming proposition which stifles the ability of our program to provide Hope, Care, and Cures to our children who need us most. Our success is measured in clinical outcomes. The nature of our work requires team members who thrive in a team-oriented, challenging, and fast paced environment. Candidates who are motivated by the concept that their individual contributions to a team will have direct clinical impact will be successful in this role.
Specifically, we are currently seeking Manufacturing Associates to join our manufacturing team. You will work alongside a team utilizing state of the art machinery in a GMP environment to manufacture cutting-edge therapies in a growing organization with an incredible mission. Your expertise running and designing processes using single-use bioreactors will help our program grow, and you will gain experience in a wide variety of manufacturing functions to grow your skillset and career. Above all, a willingness to learn, passion for our mission, and creativity are crucial for success at SCTx. We are looking forward to meeting you!
Seattle Children’s Employer Highlights:
• Leader in Pediatric Care: Because of our people, Seattle Children’s is recognized as a leading teaching, research and specialty care center at the forefront of pediatric care.
• Competitive Benefits: We support a healthy work–life balance. Our benefits include employee care, paid time off, health insurance and retirement savings.
• Transportation Discounts: Company bike program, on-site zip cars, unlimited ORCA transit pass, daily commute bonus provided to staff who us alternate methods of travel to/from work, company vanpools.
• Diversity/Inclusion: We strive to maintain an atmosphere that reflects our values of inclusion by providing effective and respectful care compatible with each patient and family's beliefs, values, and heritage.
Seattle Children's Therapeutics (SCTx) at Seattle Children's Research Institute (SCRI) is an exciting new venture aimed at leveraging a biotech industry business model in a non-profit context to bring cutting edge, curative technologies and therapies to defeat pediatric cancer and beyond. Our immunotherapies offer hope to families who have exhausted other treatment options - our work saves lives. This position will support the GMP Biologics Manufacturing team as we aim to develop our internal manufacturing capabilities for key starting materials to accelerate our cell therapy manufacturing program, including viral vectors, plasmids, and protein therapeutics.
The focus of the GMP Biologics Manufacturing team is to build an internal CDMO function to eliminate our biggest hurdle to delivering cures to kids. The sourcing of viral vectors is an expensive and time-consuming proposition which stifles the ability of our program to provide Hope, Care, and Cures to our children who need us most. Our success is measured in clinical outcomes. The nature of our work requires team members who thrive in a team-oriented, challenging, and fast paced environment. Candidates who are motivated by the concept that their individual contributions to a team will have direct clinical impact will be successful in this role.
Specifically, we are currently seeking a GMP Supervisor to join our manufacturing team. You will work alongside a team utilizing state of the art machinery in a GMP environment to manufacture cutting-edge therapies in a growing organization with an incredible mission. Your expertise running and designing processes using single-use bioreactors will help our program grow, and you will gain experience in a wide variety of manufacturing functions to grow your skillset and career. Above all, a willingness to learn, passion for our mission, and creativity are crucial for success at SCTx. We are looking forward to meeting you!
Seattle Children’s Employer Highlights:
• Leader in Pediatric Care: Because of our people, Seattle Children’s is recognized as a leading teaching, research and specialty care center at the forefront of pediatric care.
• Competitive Benefits: We support a healthy work–life balance. Our benefits include employee care, paid time off, health insurance and retirement savings.
• Transportation Discounts: Company bike program, on-site zip cars, unlimited ORCA transit pass, daily commute bonus provided to staff who us alternate methods of travel to/from work, company vanpools.
• Diversity/Inclusion: We strive to maintain an atmosphere that reflects our values of inclusion by providing effective and respectful care compatible with each patient and family's beliefs, values, and heritage.
The role of the Registration Coordinator is an essential part of the patient facing registration experience by providing support and ensuring each patient encounter is positive, professional, and efficient. The primary function of this role is to create new registrations and check patients in for scheduled and walk-in clinical visits throughout the outpatient setting of the hospital. Support may be needed for Urgent Care, Radiology, and Access Clinic check-ins, operating seven days per week, during both day and evening times. Registration Coordinator duties also include: scheduling patient return visit appointments, minimizing clinic access delays, effectively communicating with patients/families, informing of and collecting signed consent for care, maintaining standards for infection prevention, and establishing systems and resources to improve processes and efficiency of the patient experience.
We are actively seeking an experienced Clinical Research Coordinator to join our team. This is part of a large NIH-funded study called ECHO PATHWAYS; the overall aim of this study is to determine how multiple exposures in utero to multiple chemical and non-chemical (i.e. psychosocial) stressors are related to childhood neurodevelopment and airway health. We will be conducting study visits (surveys, cognitive assessments, biospecimen collection) with healthy children ages 5 – 9 over the next several years. The ideal candidate for this role will be outgoing, have experience working with children and families, and strong attention to detail and organizational skills.
The coordinator in this role, under the supervision of the Research Manager and Study PI, will:
• Lead study recruitment through various methods including telephone, email, and mailings to meet rigorous enrollment goals.
• Oversee and conduct observational study visits with healthy children and a parent, including preparation study materials, coordinating, scheduling and staffing of visits, administering standardized assessments, and careful tracking of all data and biospecimen collection.
Seattle Children's Employer Highlights:
- Dedication to staff engagement and Lean principles.
- Competitive Benefits: We support a healthy work-life balance. Our benefits include employee care, paid time off, health insurance and retirement savings.
- Transportation Discounts: Company bike program, on-site zip cars, unlimited ORCA transit pass, daily commute bonus provided to staff who us alternate methods of travel to/from work, company vanpools.
- Diversity/Inclusion: We strive to maintain an atmosphere that reflects our values of inclusion by providing effective and respectful care compatible with each patient and family's.
Provide direct care and assume responsibility for the clinical management of pediatric cardiac critical care patients in the pediatric cardiac intensive care unit and as a critical care resource provider. Obtain patient histories, perform physical examinations, order, perform, and interpret diagnostic tests, prescribe medications, perform procedures, and develop treatment plans. Direct or participate in case management and continuing care. Collaborate, refer, and consult with department attending physicians, specialists, and other members of the health care team to deliver effective, efficient, safe, and high-quality care. Contribute to organizational and departmental continuous performance and quality improvement projects. Participate in education and research efforts for patients, families, and the health care team.
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