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Search Results Page 1 of 6

Job ID/Req # 2022-45569
Perform laboratory procedures as part of ongoing research projects investigating pediatric HIV infection; assist in planning research experiments, their execution and data analysis; assist others in the laboratory with problem solving and understanding molecular biology, and help maintain a constructive laboratory environment.
Location Name
307 Westlake
Status
Limited Term
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Global Infectious Disease
Hot Job
No
Job ID/Req # 2022-45520
- Responsible for managing data associated with clinical and/or research databases. - Ensure accurate data entry for selected department databases. - Provide data administration and support for faculty and staff. - Perform data quality and maintenance activities. - Assist team in developing a data integrity plan. - Audit database for missing data and identify and resolve data errors and discrepancies. - Assist in the development and production of data quality metrics. - Support and maintain applications and related data systems. - Coordinate and participate in system upgrades. - Provide data coordination through timeline adherence, department communications, and report writing. - Create, design, and produce standardized presentation-ready data quality reports. - Develop new databases as needed, including intake, problem definition, solution design, execution and delivery of desired deliverables. Examples include REDCap project design, coding of advanced logic and calculations in REDCap, data migration from other systems (e.g. Excel, Access, etc.) and creation of dynamic SQL fields in REDCap.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Research Informatics
Remote Work Percent
060
Hot Job
No
Job ID/Req # 2022-45504
The Aldinger Laboratory in the Center for Integrative Brain Research at Seattle Children’s Research Institute has an immediate opening for a Research Technician in the fields of genetics, neurodevelopment, and disease. This individual will work in a team effort to assess the impact of human genetic variation on development and disease.   Responsibilities: - Perform laboratory procedures and investigative work as part of ongoing research projects. - Perform a variety of moderately complex investigative/technical procedures. - Interpret results and determine whether they are consistent with experimental goals. - Modify experimental procedures or technique to obtain optimal experimental results. - Assist in the assembly, organization, and interpretation of data. - Assist in the planning, execution, and analysis of research experiments.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Integrative Brain Research
Hot Job
No
Job ID/Req # 2022-45503
The Aldinger Laboratory in the Center for Integrative Brain Research at Seattle Children’s Research Institute has an immediate opening for a Research Scientist in the fields of genetics, neurodevelopment, and disease. We use standard and cutting-edge genomic tools to study the role of genetic programming on brain development and the impact of genetic variation on pediatric disease. This is a unique type of position that requires significant individual initiative and motivation to learn and understand both existing and new scientific methods and knowledge. The Research Scientist will be given the opportunity and be responsible for conducting independent and creative research related to the overall mission of the laboratory. This is an ideal position for those considering graduate school in a related field or medical school in the near future.   Responsibilities: - Develop and maintain lab organization including supplies, equipment, and protocols. - Basic scientific skills including the ability to keep detailed records of experimental design, execution, and analyses. - Provide status reports to the PI on status of projects. - Present analysis findings at group meetings and national conferences, as appropriate. - Perform related duties as required. The Research Scientist will spend the majority of their time making contributions to new and on-going laboratory projects, requiring the ability to use independent judgment to address tasks and projects, and will identify and refine existing procedures and practices. Techniques used in the lab include molecular biology (cloning, PCR, RT-PCR), histology (IHC, ISH), cell culture (cell lines, stem cells), biochemistry (WB), genomics (scRNA-seq, scATAC-seq, CUT&Tag, spatial transcriptomics, long-read sequencing). Direct experience with more than one of these techniques is preferred.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Integrative Brain Research
Hot Job
No
Job ID/Req # 2022-45489
We are actively recruiting a Clinical Research Coordinator I, MA Registered to join Seattle Children's Research Institute.  Required licensure for this position would be obtained after starting employment.   The successful candidate will support our research study comparing a novel smartphone-based otoacoustic emission (OAE) with a conventional OAE for screening hearing in infants less than 6 months old. We recruit directly from clinic (Craniofacial and Otolaryngology). Coordinators consent caregivers and do the conventional and smartphone OAE tests which are brief in nature. This position will partner with a Study Coordinator/Audiologist in Craniofacial on the training/testing process. Strong candidates will navigate fast-paced clinic environments, approach families while mindful of clinic flow, and are interested in working with babies.    This is a per diem role with an average of 20 hours per week, structured around when the most infants are coming to the clinics where we recruit.
Location Name
Hospital Main Campus
Status
Temporary
FTE
Per Diem (hours per bi-weekly pay periods varies)
Shift
Day Shift
Department
CoreSvcOp-Rsrch IntegrationHub
Hot Job
No
Job ID/Req # 2022-45481
We are actively seeking a Clinical Research Coordinator III to join Seattle Children's. This key position provides oversight to research staff and projects in the division of Nephrology, and specifically with the Health Information and Visualization Experience (HIVE) Lab. Our lab focuses on developing methods and technology to support clinical decision making for both patients and clincians. The successful candidate will have the experience necessary to collaborate with members of the research team, as well as work independently in the organization, implementation (including recruitment, consenting, and conducting study related procedures with study participants), and completion of  clinical research trials of the HIVE Lab. The successful candidate will oversee, create, and maintain regulatory documents, including IRB related documents; organize protocol implementation and site initiation visits; conduct routine monitoring of clinical studies; ensure that research projects are conducted in compliance with federal regulations, institutional policies/departmental guidelines and standards of Good Clinical Practice. In addition, this position will help compile and organize research data, and support the creation of research databases.
Location Name
Hospital Main Campus
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Clinical & Translational Rsrch
Hot Job
No
Job ID/Req # 2022-45480
The post-doctoral fellow will develop scientific skills as appropriate for this level of training position, and carry out research/development activities in support of assigned research projects. Responsibilities include protocol development and review, data collection and analysis, manuscript and fellowship application preparation, and training in the conduct of clinical trials and research.
Location Name
Other Off-Site Location
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Dev Biology & Regenerative Med
Hot Job
No
Job ID/Req # 2022-45478
Join a group of dedicated scientists and clinicians to study mammalian organ regeneration in the African spiny mouse (see PMIDs: 34610329; 34849462; 34561564). Perform laboratory procedures, mouse colony management, and investigative work as part of ongoing research projects.  Perform a variety of moderately complex investigative/technical procedures; interpret results and determine whether they are consistent with experimental goals; modify experimental procedures or technique to obtain optimal experimental results; assist in the assembly, organization and interpretation of data.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Dev Biology & Regenerative Med
Hot Job
No
Job ID/Req # 2022-45471
Collaborate with members of the Cancer and Blood Disorders Center clinical research team in the organization, implementation, and completion of clinical research trials. Create and maintain regulatory documents, organize protocol implementation and site initiation visits, and conduct routine monitoring of clinical studies. Ensure that research projects are conducted in compliance with federal regulations, institutional policies/departmental guidelines, and standards of Good Clinical Practice.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Clinical & Translational Rsrch
Hot Job
No
Job ID/Req # 2022-45469
Overview:   The Ma Lab seeks a motivated and eager to learn Research Scientist to join our team. We use computational and experimental systems biology to study host and pathogen responses during tuberculosis infection and treatment in primary ex vivo cellular, zebrafish, and mouse models.   As a scientist in lab, you would be performing experiments including: (1) measuring the survival and metabolic state of Mycobacterium tuberculosis (Mtb) in response to infection and drug treatment in a BSL-3 environment, (2) generating recombinant Mtb strains, (3) measuring mRNA gene expression in bacterial and mammalian cells (primarily macrophages) with RNA sequencing, (4) using DNA sequencing to perform forward-genetic screens, and (5) performing basic molecular biology and biochemistry techniques. You would also contribute to mentoring undergraduate labmates and helping with lab organization.   As part of our lab, active projects that you would work on include: (1) screening for and characterizing host and pathogen regulators that alter infection outcome in primary host cells, and (2) understanding how the Mtb transcriptional responses to individual and combination drug treatment influence the phenotypic outcomes.   Full time, 1.0 FTE position, flexible hours. Some weekend work is to be expected.
Location Name
307 Westlake
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Global Infectious Disease
Hot Job
No
Job ID/Req # 2022-45454
A fully supported Postdoctoral Scholar position is available in the *Seattle Tuberculosis Research Advancement Centers (SEA-TRACs) and the Coler Translational Research Group to characterize immune response of novel vaccines and immune pathology associated with tuberculosis and co-morbidities. Previous experience in cellular immunology, including multiparametric flow cytometry, is required.   The postdoctoral fellow will receive focused mentoring and training in laboratory and clinical settings and will develop expertise in the assessment of vaccine mediated immune responses and systems immunology. A key aspect will include combining information from multiple levels such as genes, proteins and whole cells to gain a clear, multi-scale understanding of vaccine function during infection and disease.   The fellowship is designed to prepare the post-doctoral level trainee for a career in a non-profit biotechnology- and multidisciplinary setting. Excellent organizational and communication skills are required.   Individuals from racial and ethnic groups that have been shown by the National Science Foundation to be underrepresented in health-related sciences on a national basis are encouraged to apply. The following racial and ethnic groups have been shown to be underrepresented in biomedical research: Blacks or African Americans, Hispanics or Latinos, American Indians or Alaska Natives, Native Hawaiians, and other Pacific Islanders.   Primary Responsibilities: • Assessment of cellular, molecular and computational immunological endpoints in preclinical projects • Contribute to study reports, statistical analysis plans and grant applications • Work closely under supervision to implement research projects that further the understanding and development of effective vaccines • Committed participation as a team member to support experimental design, developing immunoassay methodology following scientific literature review, quality standards and discussion with peers, as required • Responsible for following Standard Operating Procedures • Records procedures, outcomes and observations in lab notebook following established guidelines • Utilize established mathematical and scientific techniques to compile, critically analyze and interpret data • Communicate with research management on a regular basis • Prepare manuscripts for publication in peer reviewed journals • Presents research at group and internal/external scientific meetings • Contributes to maintenance of the sample repository including sample tracking procedures Knowledge, Skills and Abilities: • Work as a member of a collaborative team under general supervision • Able to use experience and judgment to plan and accomplish goals • Able to perform multiple scientific protocols and procedures • Good written and oral communication skills; ability to communicate tactfully and effectively • Experience writing manuscripts and grants helpful • Ability to work accurately with close attention to detail • Familiarity with current immunological or microbiological assays such as: Flow cytometry, ELISpots, Luminex, antibody neutralization, and ELISA • Proficiency with appropriate usage of statistical methods for data analysis • Extensive working knowledge with data analysis and graphing software such as FLowJo, Prism, and/or Jump • Ability to maintain confidentiality of sensitive information • Ability to work with co-workers and outside agencies professionally and tactfully • Possess a work ethic that includes team orientation, neatness, dependability, punctuality, and accuracy *Read more on this PDF (https://trtc.uw.edu/sites/trtc.uw.edu/files/uploads/NIAID%20TB%20centers%20-%20FINAL.pdf)
Location Name
307 Westlake
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Global Infectious Disease
Hot Job
No
Job ID/Req # 2022-45427
Seattle Children's Therapeutics (SCTx) at Seattle Children's Research Institute (SCRI) is an exciting new venture aimed at leveraging a biotech industry business model in a non-profit context to bring cutting edge, curative technologies and therapies to defeat pediatric cancer and beyond. Our immunotherapies offer hope to families who have exhausted other treatment options - our work directly saves lives.  We are seeking a bright, enthusiastic, and highly-motivated biologist to join our Research and Development group. This position contributes to a team focused on translating tumor immunotherapy from the bench into pediatric patients with cancer. We look for people who are inspired by our mission and who would fit in well with the collaborative, rigorous, and entrepreneurial spirit of our research team culture.   The primary purpose of this position is to develop and analyze the potential of lentiviral vectors carrying differentially regulated payloads, including chimeric antigen receptors (CARs), to create more efficacious cell therapies for solid tumors. Under the direction of a senior research scientist, the successful candidate will use her/his established molecular and cellular biology skill sets to create both tumor cell lines and primary T cells, and develop and implement assays to assess the cytotoxic and therapeutic potential of the T cell products, both in vitro and in vivo.  Lab techniques include basic and advanced molecular biology and operation of Incucyte, MSD, flow cytometers, cell sorters, and liquid handling robots.   The ideal candidate will have significant work experience in flow cytometry, tissue culture, molecular biology, and immunology. The candidate will be extensively involved in designing experiments, implementing new strategies, generating data, analyzing results and preparing reports, in support of funded research studies. To ensure successful project completion and teamwork, she/he must have critical thinking abilities, be able to prioritize and perform multiple tasks in a dynamic environment, meet deadlines, and must have excellent written, verbal, and interpersonal communication skills. The candidate will be required to participate and present data in weekly lab meetings, maintain an up-to-date and well-organized electronic lab notebook, and rigorously follow Good Laboratory Practice (GLP) guidelines.  Above all, a willingness to learn, passion for our mission, collaboration, and creativity are crucial for success at Seattle Children's Therapeutics (SCTx).  
Location Name
1920 Terry
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
SC Therapeutics (SCTx)
Hot Job
No
Job ID/Req # 2022-45426
Seattle Children's Therapeutics (SCTx) at Seattle Children's Research Institute (SCRI) is an exciting new venture aimed at leveraging a biotech industry business model in a non-profit context to bring cutting edge, curative technologies and therapies to defeat pediatric cancer and beyond. Our immunotherapies offer hope to families who have exhausted other treatment options - our work directly saves lives.  We are seeking a bright, enthusiastic, and highly-motivated biologist to join our Research and Development group. This position contributes to a team focused on translating tumor immunotherapy from the bench into pediatric patients with cancer. We look for people who are inspired by our mission and who would fit in well with the collaborative, rigorous, and entrepreneurial spirit of our research team culture.   The primary purpose of this position is to develop and analyze the potential of lentiviral vectors carrying differentially regulated payloads, including chimeric antigen receptors (CARs), to create more efficacious cell therapies for solid tumors. Under the direction of a senior research scientist, the successful candidate will use her/his established molecular and cellular biology skill sets to create both tumor cell lines and primary T cells, and develop and implement assays to assess the cytotoxic and therapeutic potential of the T cell products, both in vitro and in vivo.  Lab techniques include basic and advanced molecular biology and operation of Incucyte, MSD, flow cytometers, cell sorters, and liquid handling robots.   The ideal candidate will have significant work experience in flow cytometry, tissue culture, molecular biology, and immunology. The candidate will be extensively involved in designing experiments, implementing new strategies, generating data, analyzing results and preparing reports, in support of funded research studies. To ensure successful project completion and teamwork, she/he must have critical thinking abilities, be able to prioritize and perform multiple tasks in a dynamic environment, meet deadlines, and must have excellent written, verbal, and interpersonal communication skills. The candidate will be required to participate and present data in weekly lab meetings, maintain an up-to-date and well-organized electronic lab notebook, and rigorously follow Good Laboratory Practice (GLP) guidelines.  Above all, a willingness to learn, passion for our mission, collaboration, and creativity are crucial for success at Seattle Children's Therapeutics (SCTx).Overall responsibilities include acquiring an in-depth understanding of the field in which they are working, and working with the PI, as well as independently, on the planning, design, execution, trouble-shooting, and interpretation of experiments; makes detailed observations, records data and presents results; assists post docs and fellows in the day-to-day activities and interprets experiments related to assigned projects. The Research Scientist will spend the majority of their time making contributions to on-going laboratory projects, requiring the ability to use independent judgment to address tasks and projects, and will identify and refine existing procedures and practices. The incumbent may also participate in the management of a small rodent colony.  
Location Name
1920 Terry
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
SC Therapeutics (SCTx)
Hot Job
No
Job ID/Req # 2022-45406
A Research Scientist II position is available within the laboratory of Dr. Adrian Piliponsky at Seattle Children’s Research Institute, Department of Pediatrics, Pathology and Global Health, University of Washington (Seattle, WA) - Piliponsky Lab (seattlechildrens.org)   Research in Dr. Piliponsky’s lab is focused on the regulation of inflammatory processes involving mast cells and myeloid cells, including allergy inflammation and inflammation during bacterial infections.   The Research Scientist hired for the position will use an array of cellular and molecular approaches (ELISA, cell isolation, flow cytometry, histology, RNAseq and transcriptome analysis, qPCR, bacterial propagation; as well as, animal models of bacterial infection and allergic airway and skin inflammation using mast cell and basophil specific conditional mice). They will also be expected to formulate, execute, and communicate research projects.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Immunity & Immunotherapies
Hot Job
No
Job ID/Req # 2022-45404
Job Description:   Perform laboratory procedures and experiments investigating the role of the airway remodeling and the extracellular matrix (ECM) in lung disease during acute and chronic airway inflammation using ex vivo primary human cell culture models. Technical skills include human primary airway epithelial cell, lung stromal cell, and immune cell tissue culture, differentiation of airway epithelial cells at an air-liquid interface, gene knockdown using lentiviral shRNA and/or gene editing using CRISPR/Cas9 methods in primary human cell lines, microscopy (phase contrast; fluorescent), biochemical assays, RNA isolation, qPCR, protein assays and ELISA.   Work includes infection of airway epithelial cells in a BSL-2 laboratory with respiratory viruses. Work as part of a small lab with close collaboration and support of a larger group of lab technicians, students, clinical research associates, and principal investigators.   Complete daily lab tasks including design and execution of experiments, maintenance of laboratory records, and opportunities for authorship on manuscripts.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Immunity & Immunotherapies
Hot Job
No
Job ID/Req # 2022-45403
Job Description:   Perform laboratory procedures and experiments investigating the role of the airway remodeling and the extracellular matrix (ECM) in lung disease during acute and chronic airway inflammation using ex vivo primary human cell culture models. Technical skills include human primary airway epithelial cell, lung stromal cell, and immune cell tissue culture, differentiation of airway epithelial cells at an air-liquid interface, gene knockdown using lentiviral shRNA and/or gene editing using CRISPR/Cas9 methods in primary human cell lines, microscopy (phase contrast; fluorescent), biochemical assays, RNA isolation, qPCR, protein assays and ELISA.   Work includes infection of airway epithelial cells in a BSL-2 laboratory with respiratory viruses. Work as part of a small lab with close collaboration and support of a larger group of lab technicians, students, clinical research associates, and principal investigators.   Complete daily lab tasks including design and execution of experiments, maintenance of laboratory records, and opportunities for authorship on manuscripts.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Immunity & Immunotherapies
Hot Job
No
Job ID/Req # 2022-45401
This position is available to reside in one of the following states: Washington, Alaska, Montana, Georgia, Florida, and Texas.   Clinical Research Budget Analyst I is responsible for the development and negotiation of budgets for clinical trials and studies regardless of funding source that includes industry sponsors, grants, awards, fellowships, cooperatives, etc. Clinical Research Budget Analyst I reviews the Medicare coverage analysis based on available study documents, such as protocol, proposed budget, and informed consent, and captures all clinical costs and investigators and study team efforts required to carry out the study, as well as costs for ancillary services. The incumbent should be able to learn to capture all costs for procedures, labs, and other associated fees on an internal budget andto revise the proposed budget to reflect Seattle Children’s costs in the final negotiated budget. Clinical Research Budget Analyst I also communicates with the Office of Sponsored Research to ensure that all costs and subject reimbursement terms are appropriately captured in the clinical trial agreement. The incumbent will be responsible for using current and future systems used by Seattle Children’s, such as Clinical Trial Management Systems (CTMS).
Location Name
West 8th
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Research Integration Hub
INACTIVE Secondary Location(s)
US-AK | US-MT | US-GA | US-FL | US-TX
Remote Work Percent
080
Hot Job
No
Job ID/Req # 2022-45400
We are actively seeking a Research Assistant to conduct research assessments with local high school students and their families in public school and home settings. These assessments will include questionnaires, cognitive tasks, and behavioral observations. The successful candidate will observe school-based intervention programming and provide feedback to students and staff on accurate implementation of the program using standardized observer forms.   This position will require reliable transportation for travel to schools and research participant homes for data collection around King County region.
Location Name
1920 Terry
Status
Per Diem
FTE
Per Diem (hours per bi-weekly pay periods varies)
Shift
Day/Evening Shift
Department
Child Health, Behavior & Devel
Hot Job
No
Job ID/Req # 2022-45343
Provide administrative and database support for assigned program or project area.   Knowledge, Skills, and Abilities: - Proficiency in computer software applications - Good data entry and typing skills - Good communication and interpersonal skills - Ability to work independently and in a team setting - Good organizational skills, attention to detail, and thoroughness - Ability to analyze information and good decision making skills - Ability to establish and maintain productive working relationships - Results driven   Primary Job Responsibilities: - Prepares source data for computer entry by compiling and sorting information; establishing entry priorities. - Processes study documents by reviewing data for deficiencies; resolving discrepancies by using standard procedures or returning incomplete documents to the team leader for resolution. - Enters and labels data by inputting alphabetic and numeric information on keyboard. - Maintains data entry requirements by following data program techniques and procedures. - Verifies entered study document data by reviewing, correcting, deleting, or reentering data; purging files to eliminate duplication of data. - Maintains operations by following policies and procedures; reporting needed changes. - Contributes to team effort by accomplishing related results as needed. Provides clerical and administrative support as needed.
Location Name
1920 Terry
Status
Per Diem
FTE
Per Diem (hours per bi-weekly pay periods varies)
Shift
Day/Evening Shift
Department
SC Therapeutics (SCTx)
INACTIVE Secondary Location(s)
US-WA-Remote
Hot Job
No
Job ID/Req # 2022-45324
We are actively recruiting a Research Scientist II to join the Hahn Lab within Seattle Children's Integrative Brain Research department.  More information about Dr. Sihoun Hahn's research can be found here:  https://www.seattlechildrens.org/directory/sihoun-hahn/   This is a unique type of position that requires significant individual initiative and motivation to learn and understand both existing and new scientific methods and knowledge. The Research Scientist will be given the opportunity and be responsible for conducting independent and creative research related to the overall mission of the laboratory. This is an ideal position for those considering graduate school in a related field or medical school in the near future.   Overall responsibilities include acquiring an in-depth understanding of the field in which they are working, and working with the Principal Investigator, as well as independently, on the planning, design, execution, trouble-shooting, and interpretation of experiments; makes detailed observations, records data and presents results; assists post docs and fellows in the day-to-day activities and interprets experiments related to assigned projects. The Research Scientist will spend the majority of their time making contributions to on-going laboratory projects, requiring the ability to use independent judgment to address tasks and projects, perform literature search, communicate with other scientists, develop a validation plan, summarize the outline of the results, identify and refine existing procedures and practices.
Location Name
Jack R MacDonald Building
Status
Regular
FTE
1.0 FTE (80 hours per bi-weekly pay periods)
Shift
Day Shift
Department
Integrative Brain Research
Hot Job
No